Exchange is the main activity of SCORE and it takes place throughout the year. Research exchange projects designed by the program host a foreign medical student for a defined period of time. A participating student is incorporated into a research team of their choice and participates in research under the direct supervision of a tutor. The student will be guided through the basic principles of research, such as literature studies, collecting information, scientific writing, laboratory work, statistics and ethical aspects related to their discipline. At the end of the project, the student might be expected to write a short essay about his/her results and achievements.

The duration of the research project and the language are specified in the description of the project. Usually the projects last 4 to 6 weeks but some projects may last up to 6 months.

The research exchange project is usually carried out in English the language of the hosting country may also be used if specified.

The National Member Organizations (NMOs) in the IFMSA are represented in SCORE by a National Officer on Research Exchange (NORE). The NORE is responsible for the national research exchange program both on the national and international level.

The basis for an exchange is a so-called bilateral and unilateral contract that is signed by the NOREs from the two different National Member Organizations. These contracts determine which countries and how many students will be exchanged during the forthcoming year.

All countries have their own exchange conditions that define the information about the research exchange program that they provide for the incoming students. This information includes information about the available towns and periods, application documents needed, working conditions and vaccinations or required equipment, deadlines for sending the documents etc.

Other Activities SCORE participates in, include trainings in the form of SubRegional Trainings (SRTs), which are frequently organized by NMOs. SCORE also has working committees during the biannual General Assemblies of the IFMSA.